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591 articles, sorted by publication time.

Biopharma · global

Oral antifungal new drug olorofim meets Phase 3 endpoint, opening a regulatory window for invasive aspergillosis

In invasive aspergillosis, where treatment options are limited and nephrotoxicity often affects treatment decisions, F2G and Shionogi’s OASIS trial brings an oral drug with a new mechanism one step closer to a marketing application; however, the publicly available data are still topline results, and the full efficacy and safety profile remains to be disclosed at a medical meeting.

Health · global

Could Probiotics Become a Gentle Aid in Depression Treatment? Small Clinical Trial in Older Adults Offers Early Clues

A small randomized trial in India showed that adding a daily probiotic supplement to existing antidepressant treatment may give older adults with depression slightly greater improvement in mood and anxiety symptoms; however, the evidence remains preliminary and should not be interpreted as support for replacing medication or psychotherapy on one’s own.